CV
Contact Information
| Name | Alberto Marfoglia |
| Professional Title | AI & Healthcare Data Engineer | PhD Candidate |
| a.marfoglia@hotmail.it |
Professional Summary
PhD candidate in Computer Science and Engineering specializing in trustworthy AI, healthcare data engineering, and semantic interoperability. Experienced in designing and deploying real-world clinical data infrastructures, combining machine learning, knowledge graphs, HL7 FHIR, and Digital Twin technologies. Collaborates with hospitals, research institutes, and EU-connected healthcare initiatives.
Experience
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2025 - present Paris, France
Visiting PhD Researcher
Inria – HEKA Research Unit (INSERM – Université Paris Cité)
- Developed graph-based clinical outcome prediction models (GCNs, KG learning)
- Analyzed impact of clinical data standards (FHIR, OMOP, SPHN)
- Collaborated with Nantes University Hospital (CHU de Nantes) within NEUROVASC project
- Worked on explainable AI for healthcare decision support
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2025 - 2025 Bologna, Italy
ICT Research Consultant (AlmaHealthDB)
University of Bologna
- Engineered secure multi-user research infrastructure for AlmaHealthDB
- AlmaHealthDB, connected healthcare data infrastructure (IRCCS network: Rizzoli, S. Orsola-Malpighi, Institute of Neurological Sciences)
- Implemented GPU optimization, role-based access control, and secure data exchange
- Supported interoperability with regional infrastructure (Lepida S.c.p.A.)
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2024 - 2025 Remote
Topic Coordinator
Frontiers in Digital Health
- Coordinated special issue on Digital Twins in healthcare
- Managed peer-review and interdisciplinary editorial workflow
- Defined scientific scope on AI, interoperability, and patient-centered systems
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2023 - 2023 Bologna, Italy
Research Fellow
University of Bologna
- Designed FHIR-based clinical data transformation pipeline (Heal Italia)
- Developed ETL workflows for heterogeneous healthcare datasets
- Contributed to data lake and backend infrastructure design
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2023 - 2023 Fano, Italy
GenAI Research Engineer
MEBLabs
- Developed RAG pipelines using LLMs and vector databases (FAISS)
- Built semantic search systems with OpenAI API
- Deployed AI prototypes on AWS cloud infrastructure
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2020 - 2021 Cesena, Italy
Research Scholarship Holder
I-Tel S.r.l. / University of Bologna
- Designed a microservice-based interoperability platform for healthcare systems
- Implemented HL7, FHIR, and REST integration with legacy systems
- Built a hexagonal architecture for healthcare data exchange
Education
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2023 - present Bologna, Italy
PhD
University of Bologna
Computer Science and Engineering
- Trustworthy AI, clinical data harmonization, Digital Twins
- Knowledge graphs and graph learning for healthcare prediction
- Best Workshop Paper Award (IEEE PerCom DIGITA 2025)
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2020 - 2023 Cesena, Italy
MSc
University of Bologna
Computer Science and Engineering
- Thesis with Rizzoli Orthopaedic Institute (Bologna)
- Healthcare interoperability and digital modeling
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2017 - 2020 Cesena, Italy
BSc
University of Bologna
Computer Science and Engineering
- Pre-hospital trauma tracking system (clinical collaboration)
- Early graduation with honors award
Projects
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CONNECTED – Digital Twin Healthcare Platform
- Knowledge graph-driven Digital Twin architecture for healthcare
- Patient-centric APIs for clinical data integration and prediction
- Applied to stroke-risk and clinical outcome prediction benchmarks
- Publications in PerCom (2024–2025), Frontiers in Digital Health, FGCS
- Best Workshop Paper (DIGITA 2025)
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AlmaHealthDB
- Distributed healthcare research infrastructure across IRCCS hospitals (Bologna)
- Supports Rizzoli Orthopaedic Institute, S. Orsola-Malpighi, Neurological Sciences Institute
- EU-connected ecosystem (METASTRA, CPW, regional health service integration)
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FHIR Clinical Data Transformation Pipeline
- ETL pipeline for converting heterogeneous clinical datasets into HL7 FHIR
- Used in the MOTU dataset, the METASTRA project, and multi-center studies
- SNOMED CT-based semantic mapping and validation
Publications
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2026 Toward Interoperable Variable Definitions: A FHIR-Based Standardization Strategy for the METASTRA Project
Studies in health technology and informatics
Creating a semantically coherent clinical knowledge base for the METASTRA project, enabling more effective data reuse and supporting evidence generation in multicenter clinical studies.
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2026 A knowledge graph-driven framework for deploying AI-powered patient digital twins
Future Generation Computer Systems
Presents an interoperable framework for deploying AI-powered patient digital twins using semantic technologies, FHIR APIs, and automated model integration through knowledge graphs.
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2026 Challenges of health data standard adoption and usage: a systematic review
Journal of Biomedical Informatics
Systematic review analyzing adoption, implementation challenges, and practical usage of FHIR, OMOP-CDM, and openEHR across healthcare and research domains.
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2026 Clinical Data Goes MEDS? Let's OWL make sense of it
arXiv
Proposes MEDS-OWL, an ontology and RDF conversion framework enabling semantic-web interoperability and FAIR representation of MEDS clinical datasets.
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2025 Feasibility of MLOps-based healthcare pipelines in ensuring the Cybersecurity Framework
DEU
Explores integration of MLOps practices with the NIST Cybersecurity Framework for secure AI-driven healthcare systems.
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2025 A LLMOps-Driven Framework for Clinical Data Harmonization
DEU
Presents an LLMOps-based framework for automating and improving clinical data harmonization workflows.
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2025 CONNECTED: A Knowledge Graph-Driven Platform for Clinical Data Harmonization and Personalized Digital Twin-Based Healthcare
IEEE Computer Society
Introduces CONNECTED, a platform using knowledge graphs and digital twins for personalized medicine and predictive analytics.
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2025 Towards real-world clinical data standardization: A modular FHIR-driven transformation pipeline to enhance semantic interoperability in healthcare
Computers in Biology and Medicine
Proposes a modular FHIR-based pipeline for transforming clinical data into interoperable healthcare resources.
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2025 Editorial: Implementing digital twins in healthcare: pathways to person-centric solutions
Frontiers in Digital Health
Discusses challenges and opportunities of digital twins in healthcare, focusing on interoperability and patient-centric care.
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2024 Representation of Machine Learning Models to Enhance Simulation Capabilities Within Digital Twins in Personalized Healthcare
IEEE PerCom Workshops
Extends CONNECTED by integrating machine learning models into digital twins for simulation and prediction.
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2024 FHIR-standardized data collection on the clinical rehabilitation pathway of trans-femoral amputation patients
Scientific Data
Provides a 10-year FHIR-standardized clinical dataset for rehabilitation research.
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2023 CONNECTED: leveraging digital twins and personal knowledge graphs in healthcare digitalization
Frontiers in Digital Health
Introduces CONNECTED framework combining digital twins and knowledge graphs for healthcare systems.
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2023 MOTU on FHIR: A preliminary strategy to enable interoperability for retrospective dataset standardization
IEEE
Proposes a FHIR-based method for standardizing retrospective clinical datasets for interoperability.